| Karyopharm Therapeutics Inc. (KPTI) |
| Q4-CY2025 | Q3-CY2025 | Q2-CY2025 | Q1-CY2025 | Q4-CY2024 | Q3-CY2024 | Q2-CY2024 | Q1-CY2024 | Q4-CY2023 | Q3-CY2023 | Q2-CY2023 | Q1-CY2023 | Q4-CY2022 | Q3-CY2022 | Q2-CY2022 | Q1-CY2022 | Q4-CY2021 | Q3-CY2021 | Q2-CY2021 | Q1-CY2021 | Q4-CY2020 | Q3-CY2020 | Q2-CY2020 | Q1-CY2020 | Q4-CY2019 | Q3-CY2019 | Q2-CY2019 | Q1-CY2019 | Q4-CY2018 | Q3-CY2018 | Q2-CY2018 | Q1-CY2018 | Q4-CY2017 | Q3-CY2017 | Q2-CY2017 | Q1-CY2017 | Q4-CY2016 | Q3-CY2016 | Q2-CY2016 | Q1-CY2016 | Q4-CY2015 | Q3-CY2015 | Q2-CY2015 | Q1-CY2015 | Q4-CY2014 | Q3-CY2014 | Q2-CY2014 | Q1-CY2014 | Q4-CY2013 |
| Balance Sheet Date | | 2025-Sep-30 | 2025-Jun-30 | 2025-Mar-31 | 2024-Dec-31 | 2024-Sep-30 | 2024-Jun-30 | 2024-Mar-31 | 2023-Dec-31 | 2023-Sep-30 | 2023-Jun-30 | 2023-Mar-31 | 2022-Dec-31 | 2022-Sep-30 | 2022-Jun-30 | 2022-Mar-31 | 2021-Dec-31 | 2021-Sep-30 | 2021-Jun-30 | 2021-Mar-31 | | 2020-Sep-30 | 2020-Jun-30 | | | | | 2019-Mar-31 | 2018-Dec-31 | 2018-Sep-30 | 2018-Jun-30 | 2018-Mar-31 | 2017-Dec-31 | 2017-Sep-30 | 2017-Jun-30 | 2017-Mar-31 | 2016-Dec-31 | 2016-Sep-30 | 2016-Jun-30 | 2016-Mar-31 | 2015-Dec-31 | 2015-Sep-30 | 2015-Jun-30 | 2015-Mar-31 | 2014-Dec-31 | 2014-Sep-30 | 2014-Jun-30 | 2014-Mar-31 | 2013-Dec-31 |
| Fiscal Period | | Q3-FY2025 | Q2-FY2025 | Q1-FY2025 | Q4-FY2024 | Q3-FY2024 | Q2-FY2024 | Q1-FY2024 | Q4-FY2023 | Q3-FY2023 | Q2-FY2023 | Q1-FY2023 | Q4-FY2022 | Q3-FY2022 | Q2-FY2022 | Q1-FY2022 | Q4-FY2021 | Q3-FY2021 | Q2-FY2021 | Q1-FY2021 | | Q3-FY2020 | Q2-FY2020 | | | | | Q1-FY2019 | Q4-FY2018 | Q3-FY2018 | Q2-FY2018 | Q1-FY2018 | Q4-FY2017 | Q3-FY2017 | Q2-FY2017 | Q1-FY2017 | Q4-FY2016 | Q3-FY2016 | Q2-FY2016 | Q1-FY2016 | Q4-FY2015 | Q3-FY2015 | Q2-FY2015 | Q1-FY2015 | Q4-FY2014 | Q3-FY2014 | Q2-FY2014 | Q1-FY2014 | Q4-FY2013 |
| Total Assets | | 96,232,000$ | 104,879,000$ | 127,711,000$ | 164,418,000$ | 189,476,000$ | 213,977,000$ | 204,458,000$ | 240,438,000$ | 269,960,000$ | 297,830,000$ | 325,800,000$ | 358,172,000$ | 231,236,000$ | 256,478,000$ | 294,033,000$ | 305,305,000$ | 254,094,000$ | 286,567,000$ | 274,909,000$ | 313,050,000$ | 337,587,000$ | 380,011,000$ | | 294,963,000$ | | | 287,214,000$ | 341,192,000$ | 219,992,000$ | 256,589,000$ | 146,373,000$ | 180,294,000$ | 163,773,000$ | 185,750,000$ | 155,435,000$ | 180,385,000$ | 183,623,000$ | 170,897,000$ | 192,135,000$ | 215,443,000$ | 236,971,000$ | 263,293,000$ | 292,040,000$ | 220,337,000$ | 235,155,000$ | 137,679,000$ | 149,285,000$ | 158,226,000$ |
| Total Current Assets | | 89,746,000$ | 97,870,000$ | 120,238,000$ | 156,462,000$ | 184,755,000$ | 208,540,000$ | 198,366,000$ | 233,921,000$ | 263,222,000$ | 291,381,000$ | 318,541,000$ | 350,162,000$ | 222,677,000$ | 242,447,000$ | 276,533,000$ | 275,606,000$ | 241,579,000$ | 273,502,000$ | 255,511,000$ | 276,531,000$ | 285,447,000$ | 317,836,000$ | | 278,570,000$ | | | 271,435,000$ | 334,612,000$ | 211,562,000$ | 244,559,000$ | 133,313,000$ | 148,423,000$ | 121,682,000$ | 145,724,000$ | 112,230,000$ | 131,636,000$ | 130,251,000$ | 124,200,000$ | 138,142,000$ | 177,600,000$ | 198,344,000$ | 225,252,000$ | 249,319,000$ | 207,751,000$ | 231,346,000$ | 135,283,000$ | 147,566,000$ | 157,956,000$ |
| Cash and Cash Equivalents | | 37,672,000$ | 38,725,000$ | 38,783,000$ | 62,476,000$ | 72,828,000$ | 84,774,000$ | 30,628,000$ | 52,231,000$ | 43,655,000$ | 80,894,000$ | 84,062,000$ | 135,188,000$ | 71,351,000$ | 82,248,000$ | 153,256,000$ | 190,459,000$ | 137,400,000$ | 141,309,000$ | 88,471,000$ | 85,918,000$ | 82,301,000$ | 103,102,000$ | 202,247,000$ | 128,858,000$ | 168,004,000$ | 75,545,000$ | 83,506,000$ | 118,021,000$ | 101,600,000$ | 118,966,000$ | 37,499,000$ | 68,997,000$ | 54,450,000$ | 55,381,000$ | 25,577,000$ | 49,663,000$ | 43,908,000$ | 37,717,000$ | 42,188,000$ | 58,358,000$ | 43,499,000$ | 24,231,000$ | 51,453,000$ | 150,609,000$ | 227,131,000$ | 132,307,000$ | 144,893,000$ | 155,974,000$ |
| Receivables | | 31,877,000$ | 32,932,000$ | 35,243,000$ | 30,766,000$ | 31,778,000$ | 37,995,000$ | 31,082,000$ | 26,962,000$ | 37,923,000$ | 32,280,000$ | 35,200,000$ | 47,086,000$ | 27,446,000$ | 23,479,000$ | 24,992,000$ | 22,497,000$ | 18,752,000$ | 17,887,000$ | 17,843,000$ | 12,881,000$ | 11,062,000$ | 9,581,000$ | | 7,862,000$ | | | | | | | | | | | | | | | | | | | | | | | | |
| Other Current Assets | | | | | | | | | | | | | | 31,468,000$ | 32,078,000$ | 29,135,000$ | 1,528,000$ | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Assets Held for Sale in Short Term | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Total Noncurrent Assets | | 6,486,000$ | 7,009,000$ | 7,473,000$ | 7,956,000$ | 4,721,000$ | 5,437,000$ | 6,092,000$ | 6,517,000$ | 6,738,000$ | 6,449,000$ | 7,259,000$ | 8,010,000$ | 8,559,000$ | 14,031,000$ | 17,500,000$ | 29,699,000$ | 12,515,000$ | 13,065,000$ | 19,398,000$ | 36,519,000$ | 52,140,000$ | 62,175,000$ | | 16,393,000$ | | | 15,779,000$ | 6,580,000$ | 8,430,000$ | 12,030,000$ | 13,060,000$ | 31,871,000$ | 42,091,000$ | 40,026,000$ | 43,205,000$ | 48,749,000$ | 53,372,000$ | 46,697,000$ | 53,993,000$ | 37,843,000$ | 38,627,000$ | 38,041,000$ | 42,721,000$ | 12,586,000$ | 3,809,000$ | 2,396,000$ | 1,719,000$ | 270,000$ |
| Goodwill | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Other Intangible Assets | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Physical Assets | | 122,000$ | 244,000$ | 322,000$ | 400,000$ | 495,000$ | 628,000$ | 719,000$ | 606,000$ | 686,000$ | 766,000$ | 849,000$ | 1,139,000$ | 1,252,000$ | 1,395,000$ | 1,544,000$ | 1,642,000$ | 1,574,000$ | 1,755,000$ | 1,984,000$ | 2,219,000$ | 2,357,000$ | 2,592,000$ | | 3,046,000$ | | | 3,617,000$ | 3,863,000$ | 2,914,000$ | 2,611,000$ | 2,454,000$ | 2,185,000$ | 2,304,000$ | 2,473,000$ | 2,654,000$ | 2,836,000$ | 2,991,000$ | 3,170,000$ | 3,343,000$ | 3,483,000$ | 3,660,000$ | 3,234,000$ | 3,282,000$ | 2,754,000$ | 2,734,000$ | 604,000$ | 322,000$ | 240,000$ |
| Other Noncurrent Assets | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 15,000$ | | 299,000$ | 111,000$ | | | 52,000$ | | 500,000$ | 774,000$ | 675,000$ | 1,392,000$ | 997,000$ | 30,000$ |
| Assets Held for Sale in Long Term | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Total Liabilities | | 365,490,000$ | 343,805,000$ | 333,595,000$ | 350,435,000$ | 349,123,000$ | 346,117,000$ | 373,413,000$ | 376,644,000$ | 370,356,000$ | 369,078,000$ | 370,974,000$ | 374,828,000$ | 371,516,000$ | 372,816,000$ | 377,112,000$ | 384,978,000$ | 380,071,000$ | 369,699,000$ | 314,549,000$ | 262,504,000$ | 253,817,000$ | 250,212,000$ | | 245,189,000$ | | | 165,930,000$ | 158,022,000$ | 48,914,000$ | 43,117,000$ | 50,844,000$ | 50,830,000$ | 22,596,000$ | 19,036,000$ | 17,072,000$ | 18,142,000$ | 16,691,000$ | 17,331,000$ | 15,099,000$ | 17,078,000$ | 16,379,000$ | 15,966,000$ | 16,515,000$ | 13,543,000$ | 7,351,000$ | 5,999,000$ | 5,185,000$ | 3,292,000$ |
| Total Current Liabilities | | 87,157,000$ | 99,216,000$ | 90,370,000$ | 92,264,000$ | 61,493,000$ | 57,619,000$ | 65,341,000$ | 69,479,000$ | 62,079,000$ | 58,928,000$ | 61,555,000$ | 65,908,000$ | 61,761,000$ | 62,541,000$ | 66,337,000$ | 73,718,000$ | 68,866,000$ | 58,123,000$ | 62,008,000$ | 60,203,000$ | 52,630,000$ | 50,570,000$ | | 46,350,000$ | | | 43,860,000$ | 46,904,000$ | 41,567,000$ | 36,544,000$ | 46,734,000$ | 49,467,000$ | 21,155,000$ | 17,520,000$ | 15,481,000$ | 16,476,000$ | 14,952,000$ | 15,523,000$ | 13,222,000$ | 15,132,000$ | 14,440,000$ | 14,099,000$ | 14,702,000$ | 12,301,000$ | 6,234,000$ | 5,647,000$ | 5,015,000$ | 3,292,000$ |
| Accounts Payable | | 5,392,000$ | 2,597,000$ | 5,872,000$ | 5,107,000$ | 5,783,000$ | 2,797,000$ | 5,028,000$ | 3,123,000$ | 943,000$ | 2,287,000$ | 9,045,000$ | 2,773,000$ | 813,000$ | 1,694,000$ | 3,440,000$ | 1,603,000$ | 881,000$ | 2,309,000$ | 3,040,000$ | 4,450,000$ | 2,422,000$ | 1,888,000$ | | 985,000$ | | | 2,266,000$ | 4,332,000$ | 2,238,000$ | 3,794,000$ | 4,949,000$ | 5,665,000$ | 1,890,000$ | 3,247,000$ | 4,245,000$ | 4,751,000$ | 2,193,000$ | 4,063,000$ | 4,109,000$ | 3,808,000$ | 4,568,000$ | 4,469,000$ | 6,957,000$ | 6,288,000$ | 2,102,000$ | 3,456,000$ | 3,273,000$ | 1,740,000$ |
| Short Term Debt | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Short Term Capital Lease Obligations | | 922,000$ | 1,383,000$ | 927,000$ | 438,000$ | 3,668,000$ | 3,545,000$ | 3,425,000$ | 3,308,000$ | 3,195,000$ | 3,084,000$ | 2,977,000$ | 2,872,000$ | 2,770,000$ | 2,615,000$ | 2,463,000$ | 2,316,000$ | 2,163,000$ | 2,079,000$ | 1,997,000$ | 1,917,000$ | 1,847,000$ | 1,778,000$ | | 1,646,000$ | | | 1,375,000$ | | | | | | | | | | | | | | | | | | | | | |
| Other Current Liabilities | | | | | 4,772,000$ | | | | 7,123,000$ | | | | 6,407,000$ | | | | 7,624,000$ | | | | 4,150,000$ | | | | | | | | 1,556,000$ | 245,000$ | 551,000$ | 285,000$ | 293,000$ | 303,000$ | 271,000$ | 270,000$ | 551,000$ | 619,000$ | 358,000$ | 365,000$ | 301,000$ | 377,000$ | 241,000$ | 299,000$ | 309,000$ | 594,000$ | 77,000$ | 352,000$ | 155,000$ |
| Total Noncurrent Liabilities | | 278,333,000$ | 244,589,000$ | 243,225,000$ | 258,171,000$ | 287,630,000$ | 288,498,000$ | 308,072,000$ | 307,165,000$ | 308,277,000$ | 310,150,000$ | 309,419,000$ | 308,920,000$ | 309,755,000$ | 310,275,000$ | 310,775,000$ | 311,260,000$ | 311,205,000$ | 311,576,000$ | 252,541,000$ | 202,301,000$ | 201,187,000$ | 199,642,000$ | | 198,839,000$ | | | 122,070,000$ | 111,118,000$ | 7,347,000$ | 6,573,000$ | 4,110,000$ | 1,363,000$ | 1,441,000$ | 1,516,000$ | 1,591,000$ | 1,666,000$ | 1,739,000$ | 1,808,000$ | 1,877,000$ | 1,946,000$ | 1,939,000$ | 1,867,000$ | 1,813,000$ | 1,242,000$ | 1,117,000$ | 352,000$ | 170,000$ | 0$ |
| Long Term Debt | | | | | | | | | | | | | | | | | 169,293,000$ | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Long Term Capital Lease Obligations | | 6,008,000$ | 6,251,000$ | 6,485,000$ | 6,712,000$ | | 955,000$ | 1,884,000$ | 2,789,000$ | 3,668,000$ | 4,500,000$ | 5,310,000$ | 6,097,000$ | 6,863,000$ | 7,584,000$ | 8,286,000$ | 8,969,000$ | 9,633,000$ | 10,199,000$ | 10,749,000$ | 11,285,000$ | 11,797,000$ | 12,278,000$ | | 13,202,000$ | | | 14,457,000$ | | | | | | | | | | | | | | | | | | | | | |
| Other Noncurrent Liabilities | | 14,118,000$ | 8,256,000$ | 5,146,000$ | 2,430,000$ | 6,184,000$ | 4,281,000$ | 2,582,000$ | 978,000$ | 1,428,000$ | 2,435,000$ | 1,085,000$ | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 151,000$ | 170,000$ | |
| Total Equity | | (269,258,000$) | (238,926,000$) | (205,884,000$) | (186,017,000$) | (159,647,000$) | (132,140,000$) | (168,955,000$) | (136,206,000$) | (100,396,000$) | (71,248,000$) | (45,174,000$) | (16,656,000$) | (140,280,000$) | (116,338,000$) | (83,079,000$) | (79,673,000$) | (125,977,000$) | (83,132,000$) | (39,640,000$) | 50,546,000$ | 83,770,000$ | 129,799,000$ | 166,147,000$ | 49,774,000$ | 59,870,000$ | 82,469,000$ | 121,284,000$ | 183,170,000$ | 171,078,000$ | 213,472,000$ | 95,529,000$ | 129,464,000$ | 141,177,000$ | 166,714,000$ | 138,363,000$ | 162,243,000$ | 166,932,000$ | 153,566,000$ | 177,036,000$ | 198,365,000$ | 220,592,000$ | 247,327,000$ | 275,525,000$ | 206,794,000$ | 227,804,000$ | 131,680,000$ | 144,100,000$ | 154,934,000$ |
| Equity to Minority | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Equity to Common Shareholders | | (269,258,000$) | (238,926,000$) | (205,884,000$) | (186,017,000$) | (159,647,000$) | (132,140,000$) | (168,955,000$) | (136,206,000$) | (100,396,000$) | (71,248,000$) | (45,174,000$) | (16,656,000$) | (140,280,000$) | (116,338,000$) | (83,079,000$) | (79,673,000$) | (125,977,000$) | (83,132,000$) | (39,640,000$) | 50,546,000$ | 83,770,000$ | 129,799,000$ | 166,147,000$ | 49,774,000$ | 59,870,000$ | 82,469,000$ | 121,284,000$ | 183,170,000$ | 171,078,000$ | 213,472,000$ | 95,529,000$ | 129,464,000$ | 141,177,000$ | 166,714,000$ | 138,363,000$ | 162,243,000$ | 166,932,000$ | 153,566,000$ | 177,036,000$ | 198,365,000$ | 220,592,000$ | 247,327,000$ | 275,525,000$ | 206,794,000$ | 227,804,000$ | 131,680,000$ | 144,100,000$ | 154,934,000$ |
| Additional Paid-In Capital | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 345,166,000$ | 340,219,000$ | 224,371,000$ | 220,360,000$ | 217,500,000$ |
| Retained Earnings | | (1,657,301,000$) | (1,624,174,000$) | (1,586,922,000$) | (1,563,460,000$) | (1,532,680,000$) | (1,500,608,000$) | (1,524,400,000$) | (1,487,038,000$) | (1,445,201,000$) | (1,410,695,000$) | (1,378,065,000$) | (1,343,939,000$) | (1,305,433,000$) | (1,269,109,000$) | (1,220,047,000$) | (1,178,648,000$) | (1,217,368,000$) | (1,165,556,000$) | (1,111,974,000$) | (1,069,611,000$) | (1,026,190,000$) | (972,695,000$) | | (873,338,000$) | | | (739,909,000$) | (673,748,000$) | (615,538,000$) | (567,454,000$) | (533,800,000$) | (495,341,000$) | (456,300,000$) | (425,660,000$) | (396,275,000$) | (366,104,000$) | (339,169,000$) | (313,744,000$) | (283,586,000$) | (256,527,000$) | (227,481,000$) | (197,108,000$) | (164,412,000$) | (138,346,000$) | | | | (62,569,000$) |
| Treasury Stock | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Capital Lease Obligations | | | | | 7,150,000$ | | | | 6,097,000$ | | | | 8,969,000$ | | | | 11,285,000$ | | | | | | | | | | | 15,832,000$ | | | | | | | | | | | | | | | | | | | | | |